Manifest of the
European Network for the Diagnostics of "Imported" Viral Diseases (ENIVD)




Through Ebola epidemics in Zaire and Gabon over the past two years, we all became aware that dangerous infections could be imported to Europe in a very short time. Because of such emerging problems and due to the great number of viral pathogens it is necessary to establish a European network of collaboration in this field. The improvement of diagnostics of these "imported" and emerging virus infections is the most important step in detecting the pathogens and dealing with them. Therefore there should be a European collaboration in the area of diagnostics of these virus infections.
In fourteen meetings scientists from laboratories working in the field of diagnostics of "imported" viral diseases in Austria, Belgium, Bosnia and Herzegovina, Bulgaria, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Netherlands, Norway, Poland, Portugal, Slovakia, Slovenia, Spain, Sweden, Switzerland, and the United Kingdom have build up a network to improve the diagnostics of "imported" viral infections and have worked out objectives to be addressed in this collaboration:


1. Build a network of European laboratories working on diagnostics of "imported", rare and emerging viral infections. Provide mutual help in the exchange of diagnostic samples, i.e. sera, viruses, methods, and information in order to improve diagnostics.
2. Identify those viral infections more likely to be imported and co-ordinate the objectives and identify laboratories, capable and willing to perform the rapid diagnostics (<24h) of an acute case, suspected to be infected with a viral haemorrhagic fever.
3. Work out recommendations for standardisation and quality control in diagnostics laboratories involved in the diagnostics of such diseases.
4. Identify and operate standard assays according to defined quality control criteria.
5. Optimise limited resources by exchanging reagents, methodologies, and expertise.
6. Encourage regular contact within the network through meetings, exchange and training of laboratory personnel.
7. Open the network for members of other European laboratories.
8. Organise and co-ordinate international activities with the "Surveillance network group", the "Task force on vaccines and viral diseases", or other national or international organisations like CDC and WHO.

For further development and the integration of other European members, the project needs European funding in order to establish the European network and to improve and standardise diagnostic techniques. This will offer an opportunity for technology transfer within the European community and result in a better and more efficient diagnostics in the individual countries. In the long run, this initiative offers a chance of increasing the awareness of responsible medical institutions in each country of the EU regarding the problem of emerging and re-emerging viral diseases. By creating these surveillance activities, we will be able to better recognise and respond to threatening emerging and re-emerging diseases in the future. In supporting this group of experts, it will be possible to initiate a co-ordinated international effort to deal with these problems. This offers the chance for future interventions and an effective and close co-operation with the WHO, and also for the future implementation of proposed activities.

We welcome this collaborative network and we are willing to participate in this "European Network for Imported Virus Diseases". We will support this initiative as much as we can and it would be a pleasure for us to be of assistance in this concerted action.






This declaration was signed by :

(N) = Nominated Laboratories

Representative Institution City / Country
Dr. Stefan Aberle Klinisches Institut für Virologie der Universität Vienna / Austria (N)
Dr. Maria João Alves Instituto Nacional de saúde Dr. Ricardo Jorge Lisbon / Portugal (N)
Prof. Antonios Antoniadis Aristotelian University of Thessaloniki Thessaloniki / Greece (N)
Dr. Tatjana Avšič-Županc University of Lubljana, Medical Faculty Lubljana / Slovenia
Dr. Stephan Becker Philips-Universität, Institut für Virologie Marburg / Germany
Dr. Jiri Beran Purkyne Military Medical Academy Hradec Králové / Czech Republic
Dr. Luigi Bertinato Regione del Veneto Venice / Italy
Dr. Michèle Bouloy Institut Pasteur Paris / France (N)
Dr. David Brown Public Health Laboratory Service London / United Kingdom
Dr. Maria Capobianchi Istituto Nazionale per le Malattie Infettive Rome / Italy (N)
Dr. Saulius Chaplinskas AIDS Center Vilnius / Lithuania (N)
Dr. Remi Charrel Unite des Virus Emergents Marseille / France
Dr. Pascal Cherpillod University Hospitals of Geneva Geneva / Switzerland (N)
Dr. Jeff Connell National University of Ireland Dublin / Ireland
Dr. Juan Garcia Costa Laboratorio de Microbiologia Orense / Spain
Dr. Iva Christova National Center for Infectious & Parasitic Diseases Sofia / Bulgaria
Dr. Christian Drosten Bernhard-Nocht-Institut für Tropenmedizin Hamburg / Germany
Dr. Olivier Engler Spiez Laboratory Spiez / Switzerland
Dr. Ernst-J. Finke Sanitätsakademie der Bundeswehr Munich / Germany
Dr. Anders Fomsgaard Statens Serum Institut Copenhagen / Denmark (N)
Dr. Marie Claude Georges Institut Pasteur Lyon / France
Dr. Robin Gopal Public Health Laboratory Service London / United Kingdom
Paul Heyman Research Laboratory for Vector-Borne Diseases Brussels / Belgium (N)
Prof. Mirsada Hukic Clinical Centre University of Sarajevo Sarajevo / Bosnia and Herzegovina
Dr. Olav Hungnes Norwegian Institute Of Public Health Oslo / Norway
Dr. Janusz Kocik Military Institute of Hygiene and Epidemiology Warszawa / Poland
Dr. Marion Koopmans Rijksinstituut vor Volksgezondheid Bilthoven / Netherlands
Dr. Leondios Kostrikis University of Cyprus Nicosia / Cyprus
Dr. Milan Labuda Institute of Virology, Slovak Academy of Sciences Bratislava / Slovakia
Dr. Florigio Lista Army Medical and Veterinary Research Center Rome / Italy
Dr. Graham Lloyd Health Protection Agency Salisbury / United Kingdom
Dr. Åke Lundkvist Karolinska Institute Stockholm Stockholm / Sweden
Dr. Hermann Meyer Sanitätsakademie der Bundeswehr Munich / Germany
Dr. Loredana Nicoletti Istituto Superiore di Sanitá Rome / Italy
Dr. Matthias Niedrig Robert Koch-Institut Berlin / Germany (N)
Prof. Anna Papa Aristotelian University of Thessaloniki Thessaloniki / Greece (N)
Dr. Baiba Rozentale Infectology Center of Latvia Riga / Latvia (N)
Dr. Detlev Schultze Institut für Klinische Mikrobiologie und Immunologie St. Gallen / Switzerland
Dr. Marc Strasser Spiez Laboratory Spiez / Switzerland
Dr. Marek Tomasz Szkoda Department of Virology NIH Warszawa / Poland
Dr. Antonio Tenorio Centro Nacional de Microbiologia Majadahonda / Spain (N)
Dr. Hugues Tolou Institut de Médecine Tropicale du service de santé des armées Marseille / France
Prof. Antti Vaheri University of Helsinki, Dept. of Virology Helsinki / Finland (N)
Dr. Frank Vandenbussche CODA-CERVA-VAR Brussels / Belgium
Dr. Christian Vandenvelde Research Laboratory for Vector-Borne Diseases Brussels / Belgium (N)
Dr. Marjan van Esbroeck Instituut voor Tropische Geneeskunde Antwerp / Belgium (N)
Dr. Ildikó Visontai National Centerfor Public Health Budapest / Hungary (N)
Dr. Hana Zelená ZÚ se sídlem v Ostravě Ostrava / Czech Republic
Dr. Hervé Zeller Institut Pasteur Paris / France

Honorary Members
Dr. Jean-Paul Durand Institut de Médecine Tropicale du service de santé des armées Marseille / France
Prof. Armindo Filipe Instituto Nacional de saúde Dr. Ricardo Jorge Lisbon / Portugal
Dr. Bernard LeGuenno Institut Pasteur Paris / France
Prof. Herbert Schmitz Bernhard-Nocht-Institut für Tropenmedizin Hamburg / Germany
Prof. Guido van der Groen Institute of Tropical Medicine, Dept. of Microbiology Antwerp / Belgium

Former Members
Dr. Blenda Böttiger Statens Serum Institut Copenhagen / Denmark
Dr. David Coates Microbiological Facilities, DERA Salisbury / United Kingdom
Dr. Vincent Deubel Institut Pasteur Lyon / France
Dr. Fredrik Elgh Swedish Institute of Infectious Disease Control Stockholm / Sweden
Dr. Andrew Falconar London School of Hygiene and Tropical Medicine London / United Kingdom
Dr. Heinz Feldmann Philips-Universität, Institut für Virologie Marburg / Germany
Dr. Jan Groen Erasmus University, Dept. of Virology Rotterdam / Netherlands
Prof. William W. Hall National University of Ireland Dublin / Ireland
Dr. Susan Fisher-Hoch Fondation Mérieux Lyon / France
Dr. Valerija Kilciauskiene Center for Communicable Diseases; Prevention and Control Vilnius / Lithuania
Dr. Bernadette Murgue Institut Pasteur Paris / France
Prof. Bo Niklasson Swedish Institute of Infectious Disease Control Stockholm / Sweden
Dr. David Pulford DSTL Salisbury / United Kingdom
Prof. Günter Siegl Institut für Klinische Mikrobiologie und Immunologie St. Gallen / Switzerland
Prof. Guido van der Groen Institute of Tropical Medicine, Dept. of Microbiology Antwerp / Belgium

Updated: 08 August 06